Mariota suffered the hamstring injury on his second-quarter touchdown run in the Titans' 57-14 loss to the Texans on Sunday.
Mariota may have avoided a major injury, but Mularkey mentioned that the team is looking into adding another quarterback to its roster this week, which doesn't necessarily bode well for Mariota's status Sunday against the Dolphins.
Cassel was Mariota's backup last season and started for Tennessee in the one game Mariota missed.
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Weeden was a first-round pick (22 overall) by Cleveland in 2012 but has been with three different organizations in five years. In 2015 Cassel started in eight of the 10 games he appeared in. So far this year he has completed 60% of his passes for 792 yards and three touchdowns while rushing for 116 yards and three more scores.
NASHVILLE, Tenn. - Titans quarterback Marcus Mariota was diagnosed with a minor strained hamstring following an MRI.
The Titans, who visit Miami (1-2) on Sunday, also waived linebacker Josh Carraway and swapped wide receiver C.J. Board onto the practice squad with cornerback Kenneth Durden released. If Mariota can't play in Week 5 against the Dolphins, Matthews will be hard to trust as more than a boom-bust WR3/4.